    Project 3, Morphological Visualization and Assessment:

        Explore the envelope of tissue surrounding stimulation,
        recording and/or chemical delivery probes for histological
        evidence of deterioration of probe performance which has been
        observed electrophysiologically in vivo.

    Collaborative Research Projects

    In addition to internal projects, there are multiple collaborative
    research projects with investigators outside the Center.
    Collaborators contribute significantly toward improving and expanding
    the use of the technology in areas including optimization of device
    designs, evaluation of chronic connectors, interconnects and cranial
    chambers, improvement of implantation methods, development of
    protocols for chronic electrode site maintenance, testing of advanced
    devices, and exploration of new application areas.

    Here are links to webpages of some of our collaborators (more to come.....):

    http://osiris.rutgers.edu/Buzsaki.html

        Gyorgy Buzsaki, M.D., Ph.D., Rutgers University, Neural network
        activity in the hippocampal formation

    http://www.dbbs.wustl.edu/RIB/Highstein.html

        Steven Highstein, M.D. Ph.D., Washington University, Effects of
        microgravity upon the labyrinth

    http://msewww.engin.umich.edu/people/milty/protein_polymers.html

        David Martin, Ph.D., University of Michigan, Microstructure and
        processing of bioactive protein polymers

    http://www.med.umich.edu/khri/censys/jmiddleb.htm

        John Middlebrooks, Ph.D., University of Michigan, Cortical
        representation of auditory space

    Service to investigators outside of the CNCT is provided in the forms
    of distribution of probes, and training in their use.

    Distribution has been a key component of the CNCT since its
    inception.  In fact, it provided the main motivation for applying for
    the first NIH NCRR grant in 1994. To receive probes, we require that
    investigators fill out an application.  Details of the variety of
    devices which we offer to the research public are outlined in a
    catalog. Standard devices are provided packaged appropriate for acute

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